Table 3.
Correlation analysis of CSF biomarkers in HHV-6 encephalopathy.
| Biomarker | 8-OHdG | HEL | Tau | IL-6 | IL-10 | TNF-α | |
|---|---|---|---|---|---|---|---|
| 8-OHdG | Spearman r | 1.000 | −0.292 | −0.239 | −0.484 | −0.046 | −0.315 |
| P | <0.0001 | 0.312 | 0.373 | 0.068 | 0.871 | 0.253 | |
|
| |||||||
| HEL | Spearman r | −0.292 | 1.000 | 0.277 | 0.476 | −0.286 | 0.497 |
| P | 0.312 | <0.0001 | 0.338 | 0.086 | 0.322 | 0.070 | |
|
| |||||||
| Tau | Spearman r | −0.239 | 0.277 | 1.000 | −0.036 | −0.224 | 0.091 |
| P | 0.373 | 0.338 | <0.0001 | 0.899 | 0.422 | 0.748 | |
|
| |||||||
| IL-6 | Spearman r | −0.484 | 0.476 | −0.036 | 1.000 | 0.226 | 0.783 |
| P | 0.068 | 0.086 | 0.899 | <0.0001 | 0.418 | 0.0006 | |
|
| |||||||
| Il-10 | Spearman r | −0.046 | −0.286 | −0.224 | 0.226 | 1.000 | 0.166 |
| P | 0.871 | 0.322 | 0.422 | 0.418 | <0.0001 | 0.555 | |
|
| |||||||
| TNF-α | Spearman r | −0.315 | 0.497 | 0.091 | 0.783 | 0.166 | 1.000 |
| P | 0.253 | 0.070 | 0.748 | 0.0006 | 0.555 | <0.0001 | |
CSF: cerebrospinal fluid; HHV: human herpesvirus; 8-OHdG: 8-hydroxy-2′-deoxyguanosine; HEL: hexanoyl-lysine adduct; IL: interleukin; TNF: tumor necrosis factor.