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. 2014 Sep 25;8(9):e3194. doi: 10.1371/journal.pntd.0003194

Figure 8. IL-12 is up-regulated at the transcriptional level in BMM from cathepsin B-deficient mice in response to L. major infection and LPS stimulation.

Figure 8

Relative expression levels of (A) IL-12p40 and (B) IL-12p35 transcripts in mRNA from BMM at 6 hours or 24 hours p.i. with L. major promastigotes or LPS stimulation. Non-treated (NT) BMM from each mouse line were used as negative controls. The expression levels were estimated using the 2− ΔΔC T method, using WT NT BMM at t = 6 hours as a reference. The results are shown as mean ± SD of 4 independent experiments, * p<0.05.