Table 1. Demographic characteristics of patients with positive isolates for imipenem-resistant Acinetobacter baumannii (IRAB).
Variable | No of patients (%) n = 40 |
Age (years), mean ± SD | 69.2±16.3 |
Male (%) | 24 (60.0) |
Underlying disease | |
Diabetes mellitus | 14 (35.0) |
Cancer | 13 (32.5) |
Stroke | 7 (17.5) |
Chronic kidney disease | 5 (12.5) |
Liver cirrhosis | 4 (10.0) |
Connective tissue disease | 2 (5.0) |
Use of steroid | 6 (15.0) |
Use of immunosuppressant | 4 (10.0) |
Site of isolates | |
Endotracheal aspirate | 30 (75.0) |
Catheter tip | 4 (10.0) |
Blood | 3 (15.0) |
Urine | 2 (5.0) |
Wound | 2 (5.0) |
Device | |
Endotracheal tube | 37 (92.5) |
Central venous catheter | 32 (80.0) |
Port-A catheter | 7 (17.5) |
Double lumen catheter | 4 (10.0) |
AV shunt | 1 (2.5) |
Abdominal drainage | 4 (10.0) |
Pleural drainage | 2 (5.0) |
Total parenteral nutrition | 3 (7.5) |
Previous use of antibiotic in the preceding 90 days | |
Fluoroquinolones | 27 (67.5) |
Carbapenem | 17 (42.5) |
Extended-spectrum cephalosporin | 16 (40.0) |
Extended-spectrum β-lactam-β-lactamase inhibitor combinations | 7 (17.5) |
Hospital stay before acquisition of IRAB (days) | 14.4±9.4 |
ICU stay before acquisition of IRAB (days) | 10.1±5.5 |
Clinical significance | |
Colonization | 22 (55.0) |
Ventilator associated pneumonia | 15 (30.0) |
Central venous catheter related infection | 2 (10.0) |
Skin and soft tissue infection | 1 (5.0) |
Outcome | |
In-hospital mortality | 10 (25.0) |