Table 4. Samples evaluated for FcεRI expression using the proximity ligation assay.

	peripheral blood a		lesional biopsy
	FcεRI/IgE	FcεRIα/FcεRIβ	FcεRIα/IgE	FcεRIα/FcεRIβ	totalIgEb	BP180-IgEc	eosinophilcount	diseaseactivityd
BP456	+	–	+++	+++	538	30.78	130	0/2
BP470	+	–	+	+	408	152.6	720	3/75
BP474	–	–	+	+	34	115.2	490	5/83
BP 482	++	–	+++	–	124	99.2	530	3/40
BP485	–	–	–	–	166	15.4	NDe	4/12

^aeosinophils were enriched from peripheral blood using density centrifugation and adhered to glass slides.

^bexpressed as IU of IgE, normal range ≤100 IU.

^cELISA Index Value, normal range ≤19.

^dreported as BP index/BPDAI as described in the Methods.

^enot done.