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. Author manuscript; available in PMC: 2015 Oct 1.
Published in final edited form as: Biochim Biophys Acta. 2014 May 4;1839(10):939–950. doi: 10.1016/j.bbagrm.2014.04.019

Figure 2.

Figure 2

Predicted secondary structure, sequence conservation, and gene regulatory mechanism of PreQ1 riboswitches. (A,B) Sequence conservation of riboswitch aptamer domains of PreQ1-I (A) and PreQ1-II (B). Sequence conservation is from 894 sequences from 647 species for PreQ1-I and 429 sequences from 423 species for PreQ1-II from the Rfam database (1/31/2014) http://rfam.sanger.ac.uk/. (C,D) Schematic of gene regulation by PreQ1-I riboswitches for (C) transcription or (D) translation. The antiterminator in (C) and mechanism for regulation were revealed from structural studies [45, 46].