Table 5.
Comparing PD and control subjects by gender using 2-way ANOVA: group means, standard deviations, F statistic and p values for select clinical measures and iTUG and iSway diagnosis prediction variables.
| PD Men (N=77) |
PD Women (N=58) |
Control Men (N=27) |
Control Women (N=39) |
F diagnosis |
p-val diagnosis |
F gender |
p-val gender |
F interaction |
p-val interaction |
||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Measure | Mean | SD | Mean | SD | Mean | SD | Mean | SD | |||||||
| Age | 63.51 | 10.27 | 64.65 | 9.37 | 63.40 | 10.59 | 62.65 | 8.83 | 0.50 | 0.480 | 0.020 | 0.900 | 0.400 | 0.527 | |
| MDS-UPDRS part III | 26.86 | 13.02 | 25.05 | 12.54 | 0.417 | ||||||||||
| MDS-UPDRS part III PIGD subscore | 2.08 | 2.02 | 2.64 | 2.80 | 0.180 | ||||||||||
| iTUG | Turn To Sit: Peak Turn Velocity | 143.61 | 35.67 | 160.49 | 40.28 | 167.59 | 32.49 | 185.54 | 37.55 | 15.69 | 0.000 | 11.51 | 0.001 | 0.19 | 0.666 |
| Gait: RoM Trunk horizontal [CoV] | 0.13 | 0.08 | 0.15 | 0.10 | 0.16 | 0.08 | 0.21 | 0.11 | 8.00 | 0.005 | 8.30 | 0.004 | 1.83 | 0.177 | |
| Gait: Stride Length [Mean] | 79.36 | 7.79 | 75.49 | 10.76 | 82.17 | 5.89 | 82.57 | 5.79 | 15.06 | 0.000 | 1.90 | 0.170 | 2.67 | 0.104 | |
| Turn: Number of steps [Mean] | 5.27 | 1.23 | 5.12 | 1.20 | 4.56 | 0.97 | 4.46 | 1.23 | 12.82 | 0.000 | 0.59 | 0.444 | 0.00 | 0.985 | |
| Gait: Peak Swing Velocity R [CoV] | 0.05 | 0.02 | 0.05 | 0.03 | 0.04 | 0.01 | 0.04 | 0.01 | 6.71 | 0.010 | 0.02 | 0.882 | 1.34 | 0.248 | |
| Turn: Duration [Mean] | 2.71 | 0.75 | 2.56 | 0.68 | 2.44 | 0.61 | 2.16 | 0.54 | 9.00 | 0.003 | 5.49 | 0.020 | 0.83 | 0.365 | |
| Turn To Sit: RoM Trunk | 21.72 | 6.38 | 21.91 | 8.38 | 23.32 | 8.26 | 27.68 | 10.70 | 8.12 | 0.005 | 3.48 | 0.064 | 2.95 | 0.088 | |
| Gait: RoM Knee [Mean] | 53.72 | 4.83 | 53.13 | 6.03 | 56.19 | 4.93 | 56.04 | 4.42 | 11.19 | 0.001 | 0.18 | 0.672 | 0.10 | 0.754 | |
| Gait: RoM Knee R [Mean] | 50.43 | 5.56 | 51.54 | 7.87 | 53.01 | 5.51 | 54.99 | 5.78 | 9.79 | 0.002 | 2.20 | 0.139 | 0.14 | 0.714 | |
| Turn: Peak Velocity [Mean] | 139.79 | 34.79 | 146.34 | 32.80 | 154.09 | 30.77 | 164.17 | 31.55 | 8.94 | 0.003 | 3.08 | 0.081 | 0.23 | 0.632 | |
| Wilks’ lambda | 4.80 | <.0001 | 6.75 | <.0001 | 1.37 | 0.189 | |||||||||
| iSway | Path length | 7.10 | 7.98 | 10.84 | 13.91 | 5.29 | 1.49 | 5.02 | 1.49 | 7.72 | 0.006 | 1.590 | 0.209 | 2.12 | 0.147 |
| High frequency power (AP) | 14.95 | 14.72 | 15.46 | 18.77 | 9.11 | 6.81 | 9.81 | 6.24 | 7.13 | 0.008 | 0.080 | 0.780 | 0.00 | 0.965 | |
| Mean distance (ML) | 0.02 | 0.02 | 0.03 | 0.04 | 0.01 | 0.01 | 0.02 | 0.01 | 10.14 | 0.002 | 4.270 | 0.040 | 2.78 | 0.097 | |
| Normalized jerk (AP) | 1.24 | 0.52 | 1.17 | 0.43 | 1.16 | 0.24 | 1.01 | 0.19 | 3.53 | 0.062 | 3.020 | 0.084 | 0.44 | 0.507 | |
| Path length (AP) | 4.71 | 3.19 | 7.72 | 9.90 | 3.98 | 1.33 | 3.86 | 1.20 | 6.94 | 0.009 | 2.740 | 0.099 | 3.20 | 0.075 | |
| Mean frequency | 0.57 | 0.30 | 0.53 | 0.25 | 0.53 | 0.14 | 0.44 | 0.10 | 3.24 | 0.073 | 3.020 | 0.084 | 0.67 | 0.414 | |
| Normalized jerk | 5.45 | 2.63 | 4.99 | 1.46 | 5.09 | 0.94 | 4.47 | 0.74 | 2.39 | 0.124 | 3.580 | 0.060 | 0.08 | 0.778 | |
| Range of acceleration | 0.39 | 0.22 | 0.60 | 0.51 | 0.36 | 0.13 | 0.38 | 0.14 | 6.44 | 0.012 | 5.870 | 0.016 | 3.61 | 0.059 | |
| Total sway area | 0.01 | 0.01 | 0.02 | 0.06 | 0.00 | 0.00 | 0.00 | 0.00 | 4.78 | 0.030 | 2.510 | 0.115 | 2.57 | 0.111 | |
| Mean velocity (ML) | 0.04 | 0.03 | 0.06 | 0.06 | 0.03 | 0.02 | 0.03 | 0.02 | 6.80 | 0.010 | 5.73 | 0.018 | 2.27 | 0.134 | |
| Wilks’ lambda | 1.89 | 0.043 | 2.25 | 0.014 | 0.57 | 0.849 | |||||||||