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. 2014 Sep 25;10(9):e1004380. doi: 10.1371/journal.ppat.1004380

Figure 6. Combined assessment of co-inhibitory molecule expression and differentiation state.

Figure 6

CD8 T-cell differentiation and CD8 T-cell expression of 2B4, CD160 and/or PD-1 were analyzed. (A) Representative example of flow cytometric profile of CD8 T-cell subsets defined by CCR7 and CD45RA expressing 2B4 and/or CD160. (B) Cumulative analyses (n = 10) of co-inhibitory molecules expression within 3 distinct memory CD8 T-cell subsets. (C) Cumulative analyses (n = 10) of the differentiation within 6 distinct CD8 T-cell population defined by 2B4, PD-1 and CD160 expression. NS: not significant. Statistical significance (P values) was obtained using One-way ANOVA (Kruskal-Wallis test) followed by a paired Student's t-test. Red bars correspond to mean ± SEM. Red stars indicate statistical significance (P<0.05).