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. 2014 Sep 26;9(9):e107213. doi: 10.1371/journal.pone.0107213

Table 1. DM199 dosing regimen and study cohort details.

Dose Group1 , 2 , 3 DM199 dose (Units/kg) Treatment Frequency Treatment group name
1 None Daily Vehicle
2 2 Daily 2 U/kg/day
3 40 Daily 40 U/kg/day
4 100 Daily 100 U/kg/day
5 100 Thrice weekly 100 U/kg/3x-week
6 100 Once weekly 100 U/kg/1x-week
1

Cohort 1: All dose groups; 18-week treatment.

2

Cohort 2: All dose groups; 10-week treatment.

3

Cohort 3: Dose groups 1 & 4; 9-week treatment.