Table 3. Interaction SNPs detected among CHRNB2, NTRK2, BDNF, and CHRNA4.
Modela | TAb | p sign valuec | p perm valued |
rs2072660-rs1209068-rs11030134-rs6011770 | |||
GEE-GMDR | .5780 | <10e-04 | 2.62e-04 |
GMDR FTND e | .5411 | 6.30e-02 | 9.87e-02 |
GMDR ND f | .5283 | 2.41e-02 | 2.40e-01 |
GMDR MC g | .5128 | 5.40e-01 | 7.86e-01 |
In the model, from left to right, the SNPs are located in CHRNB2, NTRK2, BDNF, CHRNA4, respectively.
TA denotes test accuracy.
p sign values were from the sign test after Bonferroni correction.
p perm values were from the permutation test after Bonferroni correction.
FTND denotes the Fagerstrom Test for Nicotine Dependence.
ND denotes the DSM4 Nicotine Dependence.
MC denotes the Maximum number of Cigarette.