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. 2014 Sep 26;9(9):e108002. doi: 10.1371/journal.pone.0108002

Table 4. Synthesis of concepts, with second and third order interpretations.

Concepts Second order interpretations Third order interpretations
Experiences of cognitive changes: Trajectory of cognitive changes, types of cognitive changes, cognitive domains affected, experiences of cognitive changes, awareness of cognitive changes. Call for help and support: Healthcare providers to inform of possible cognitive changes, respond to medical community, how to teach me, Looking for answers in all the wrong places, underwhelming information for an overwhelming experience (a) Patients want validation that it is real and to be prepared for cognitive changes; want health staff to be proactive in addressing the issue; a strategy viewed as able to reduce tension and frustration of family members also (b) The chemobrain struggle
Impact of chemobrain: Self and social relationship – how I changed, daily functioning, working life, psychosocial, financial, overall life satisfaction, change in all aspects of functioning (c) Significant impact of chemobrain phenomena on self, family, social circle, daily living and work performances. (d) The substantial impact of chemobrain across life domains
Coping: Trying my best to fit in, coping strategies, adjusting to fit in, prior needs of information on cognitive side effects (e) Ways of coping derived by survivors with multiple strategies to help themselves to overcome the phenomena. (f) Struggling to self manage (without support from health professionals)
Reflect on survivorship: Thankfulness - I am still alive, Apprehension - what the future holds. (g) Reflection on survivorship to attain normality and regain function (h) Thankful for life, yet fearful of the future

2nd order construct interpretations of participants' understandings made by authors of these studies (and usually found in the discussion and conclusion section of an article). 3rd order construct the synthesis of both first and second order constructs into a new model or theory about a phenomenon.