Table 2. The response of corticosteroid for the treatment-related pulmonary toxicities.
| Drug-induced ILD (n=88) |
Radiation pneumonitis (n=189) |
AE COPD (n=47) |
Others (n=74) |
Pa | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| No. | % | No. | % | No. | % | No. | % | ||||||
| Steroid regimenb | <0.001 | ||||||||||||
| Pulse | 22 | 25 | 5 | 3 | 0 | 0 | 7 | 10 | |||||
| High-dose | 42 | 48 | 33 | 17 | 19 | 40 | 21 | 28 | |||||
| Low-dose | 24 | 27 | 151 | 80 | 28 | 60 | 46 | 62 | |||||
| Corticosteroid response | <0.001 | ||||||||||||
| Fatal | 31 | 35 | 24 | 13 | 9 | 19 | 28 | 38 | |||||
| Recovered | 57 | 65 | 165 | 87 | 38 | 81 | 46 | 62 | |||||
Abbreviations: ILD, interstitial lung disease; AE COPD, acute exacerbation of chronic obstructive pulmonary disease. aP value was calculated by 2 test; bSteroid regimen: Pulse, ≥500 mg/day methylprenisolone for 3 days, followed by high-dose steroid; high-dose, ≥0.5 mg/kg/day prednisolone; low-dose, <0.5 mg/kg/day prednisolone.