Skip to main content
. Author manuscript; available in PMC: 2015 Mar 15.
Published in final edited form as: Cancer Res. 2014 Jul 23;74(18):5277–5286. doi: 10.1158/0008-5472.CAN-14-0053

Figure 1.

Figure 1

Runx2 expression is developmentally regulated in the mammary gland.

A) Quantitative PCR of Runx2 expression across a developmental time course (n=3 mice at each time point) P-pregnancy; L-lacation; I-involution (*** p<0.01).

B) Representative western blot of Runx2 expression of protein extracted from same tissue as mRNA used in (A).

C) Runx2 immunohistochemistry of Runx2+/+ and Runx2−/− mammary glands generated by transplantation of Runx2+/+ and Runx2−/− embryonic mammary tissue to Rag1−/− hosts. Glands collected 16 weeks post-transplantation, from virgin Rag1−/− recipient mice with cross-section of duct shown (Scale bar 50 μm).