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. 2014 Sep 29;4:6474. doi: 10.1038/srep06474

Figure 5. Functional study of the GPCR014419 gene in the permethrin resistant MAmCqG6 strain using RNAi.

Figure 5

(A). The correlation between GPCR014419 and susceptibility to permethrin was characterized by dsRNA knockdown of the GPCR014419 gene in MAmCqG6 mosquitoes compared to non-injected and GFP-injected mosquitoes. The Y-axis represents the LC50 of permethrin in dsRNA-injected and non-injected mosquitoes. (B). Relative expression of 4 cytochrome P450 genes in dsRNA of GPCR014419-injected, GFP-injected and non-injected mosquitoes. The relative gene expression shown along the Y-axis is the ratio of the gene expression in dsRNA-injected mosquitoes compared with that in non-injected ones. The results are shown as the mean ± S.E. Significant differences are indicated by *(P ≤ 0.05), **(P ≤ 0.01), and ***(P ≤ 0.001).