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. 2014 Apr 3;25(10):2351–2365. doi: 10.1681/ASN.2013070734

Table 4.

Univariate Cox analysis

Parameter Total Mortality Cardiovascular Mortality
HR (95% CI) P Value HR (95% CI) P Value
EF 0.98 (0.97 to 0.99) 0.04 0.98 (0.96 to 0.99) 0.01
SL peak G 1.13 (1.06 to 1.21) <0.0001 1.23 (1.13 to 1.35) <0.001
SL peak S 1.12 (1.05 to 1.19) 0.001 1.21 (1.10 to 1.32) <0.001
SrL peak S 1.99 (0.81 to 4.85) 0.13 8.82 (2.41 to 32.21) <0.001
SrL peak E 0.90 (0.44 to 1.82) 0.77 0.39 (0.16 to 0.98) 0.045
SrL peak A 1.16 (0.93 to 1.45) 0.20 0.16 (0.05 to 0.51) 0.002
SC peak G 1.10 (1.05 to 1.15) <0.001 1.09 (1.02 to 1.15) <0.01
SC peak S 1.1 (1.05 to 1.15) <0.001 1.09 (1.03 to 1.16) <0.01
SrC peak S 1.71 (0.96 to 3.04) 0.07 1.73 (0.78 to 3.82) 0.18
SrC peak E 0.41 (0.24 to 0.68) 0.001 0.53 (0.26 to 1.06) 0.07
SrC peak A 0.83 (0.53 to 1.30) 0.42 0.80 (0.42 to 1.51) 0.49
SR peak G 0.97 (0.96 to 0.99) 0.003 0.97 (0.95 to 0.99) 0.01
SrR peak S 0.62 (0.40 to 0.94) 0.03 0.59 (0.33 to 1.06) 0.08
SrR peak E 1.53 (1.09 to 2.17) 0.02 1.31 (0.82 to 2.10) 0.25
SrR peak A 1.37 (0.96 to 1.94) 0.08 1.13 (0.71 to 1.79) 0.61

For all strain parameters with a negative sign (i.e., SL peak G, SL peak S, SrL peak S, SC peak G, SC peak S, SrC peak S, SrR peak E, and SrR peak A), the hazard ratio is >1 because a higher value for these parameters indicates less myocardial contraction (strain) or contraction velocity (strain rate).

HR, hazard ratio; EF, ejection fraction; SL peak G, strain longitudinal peak global value; SL peak S, strain longitudinal peak systolic; SrL peak S, strain rate longitudinal peak systolic; SrL peak E, strain rate longitudinal diastolic peak E; SrL peak A, strain rate longitudinal diastolic peak A; SC peak G, strain circumferential global peak value; SC peak S, strain circumferential peak systolic value; SrC peak S, strain rate circumferential peak systolic value; SrC peak E, strain rate circumferential diastolic peak E; SrC peak A, strain rate circumferential diastolic peak A; SR peak G, strain radial peak global value; SrR peak S, strain rate radial systolic peak value; SrR peak E, strain rate radial diastolic peak E; SrR peak A, strain rate radial diastolic peak A.