Table 2.

Molecular microscope results at the time of rejection and correlations with concurrent clinical, histologic, and immunologic parameters

Parameters	ABMR Molecular Score	Endothelial DSA-Selective Transcripts
Clinical parameters
eGFR at time of biopsy, µmol/L	0.002	0.009
Proteinuria at the time of biopsy, g/L	0.030	0.076
Immunologic parameters
Class II or I DSA MFImax at the time of rejection	0.442a	0.273b
Histologic parameters
g score	0.036	0.030
ptc score	0.171	0.207
Interstitial inflammation score	−0.087	−0.031
Tubulitis score	−0.227	−0.094
Interstitial fibrosis/tubular atrophy score	0.247b	0.119
Arterial fibrous intimal thickening score	0.112	−0.084
cg score	0.135	0.242b
Mesangial matrix expansion score	0.254b	0.287b
C4d deposition in graft capillaries (C4d Banff score)	0.328b	0.181
Humoral histologic score (g+ptc+v+cg+C4d)	0.069	0.163
Molecular parameters
ABMR Molecular Score	1.000	0.737a
Endothelial DSA-selective transcripts	0.737a	1.000
NK transcripts	0.841a	0.613a
T-cell transcripts	0.123	0.172
AKI score	0.171	0.125

^aP<0.01 (Spearman correlations with Bonferroni correction for multiple comparisons).

^bP<0.05 (Spearman correlations with Bonferroni correction for multiple comparisons).