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Transcellular calcium transport is mediated by several channels, pumps, and exchangers located at the apical and basolateral portions of the cell. NaCX, Na+-Ca2+. (A) Distribution of 1α,25(OH)2D or PTH-sensitive channels and transporters along the distal convoluted tubule (DCT1 and DCT2), connecting tubule (CNT), and cortical and medullary collecting ducts (CCD and MCD). (B) Calcium transport in the DT occurs by transcellular mechanisms.
