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. 2014 Jul 14;35(10):2291–2299. doi: 10.1093/carcin/bgu147

Fig. 1.

Fig. 1.

Low CHO, high protein diets containing celecoxib reduce the growth rate of primary 4T1 Tumors. (A) Growth curve (mean tumor volume ± SEM) of injected 4T1 tumors in BALB/c mice (6 mice/group) on Western or 15% CHO chows (± 0.1% wt/wt celecoxib in the chow). (B) Size of 4T1 tumors 3 weeks postimplantation. Pooled results of three independent studies (mean indicated by line) totaling 18 mice on the Western, 12 on the 15% CHO, 12 on the Western + 0.1% celecoxib and 18 on the 15% CHO + 0.1% celecoxib chow. (C) Mean weights of 4T1 tumor-bearing mice shown in panel (A). (D) Non-fasting BG readings of ad libitum-fed mice. Pooled results from three independent studies. *P ≤ 0.05 in a t-test comparing the two indicated groups; **P ≤ 0.01 in a t-test comparing the two indicated groups; # P ≤ 0.05 in a t-test against any other group; @ P ≤ 0.06 in a t-test comparing the two indicated groups.