Table 3.
Baseline patient clinical characteristics by pre-ablation OAC
OAC before ablation | Warfarin | Aspirin |
None |
Dabigatran |
Rivaroxaban |
||||
---|---|---|---|---|---|---|---|---|---|
Number of ablations | 1113 | 472 | 136 | 426 | 187 | ||||
LA size (cm) | 4.44 ± 0.66 | 4.01 ± 0.62 | <0.0005* | 4.04 ± 0.74 | <0.0005* | 4.36 ± 0.63 | =0.031* | 4.34 ± 0.84 | =0.123 |
Age (years) | 64.5 ± 9.5 | 60.6 ± 9.6 | <0 .0005* | 58.4 ± 11.8 | <0.0005* | 64.6 ± 8.1 | <0.848 | 65.8 ± 9.6 | =0.084 |
Gender female | 28.9% | 29.4% | =0.856 | 33.1% | =0.136 | 27.5% | =0.571 | 30.5% | =0.728 |
Duration of AF (years) | 6.6 ± 7.7 | 6.7 ± 6.9 | =0.808 | 5.8 ± 6.4 | =0.181 | 5.8 ± 7.2 | =0.064 | 6.4 ± 7.0 | =0.739 |
# Drugs failed | 1.36 ± 1.12 | 1.13 ± 0.98 | <0.0005* | 1.13 ± 0.86 | =0.004* | 1.32 ± 1.09 | =0.528 | 1.18 ± 0.96 | =0.021* |
CHADS2 score | 1.12 ± 1.05 | 0.61 ± 0.81 | <0.0005* | 0.58 ± 0.84 | <0.0005* | 1.28 ± 1.07 | =0.0008 | 1.55 + 1.04 | <0.0005* |
CHA2DS2-VASC score | 1.98 ± 1.44 | 1.26 ± 1.18 | <0.0005* | 1.24 ± 1.20 | <0.0005* | 2.13 ± 1.45 | =0.068 | 2.48 + 1.46 | <0.0005* |
Hypertension | 54.8% | 38.3% | <0.0005* | 34.6% | <0.0005* | 63.3% | =0.003* | 67.4% | =0.001* |
Diabetes | 11.6% | 4.2% | <0.0005* | 4.4% | =0.012* | 16.0% | =0.026* | 16.0% | =0.09 |
BMI | 30.1 ± 5.4 | 28.8 ± 4.9 | <0.0005* | 27.9 ± 5.2 | <0.0005* | 29.9 ± 6.1 | =0.531 | 29.3 ± 5.4 | =0.061 |
Paroxysmal AF | 21.7% | 48.1% | <0.0005* | 48.9% | <0.0005* | 21.7% | =0.944 | 26.5% | =0.189 |
Persistent AF | 56.8% | 46.5% | <0.0005* | 45.9% | =0.017* | 64.1% | =0.013* | 63.5% | =0.0885 |
Long-standing AF | 21.5% | 5.1% | <0.0005* | 5.2% | <0.0005* | 14.2% | =0.002* | 9.9% | =0.001* |
Prior cardioversion | 55.9% | 27.3% | <0.0005* | 30.9% | <0.0005* | 57.0% | =0.688 | 50.8% | =0.204 |
Coronary artery disease | 16.6% | 11.2% | =0.007* | 8.8% | =0.024* | 16.2% | =0.878 | 15.6% | =0.596 |
Dilated cardiomyopathy | 10.8% | 4.2% | <0.0005* | 2.9% | =0.003* | 15.0% | =0.023* | 8.0% | =0.30 |
Prior stroke/TIA | 10.3% | 1.9% | <0.0005* | 2.3% | =0.002* | 9.1% | =0.452 | 6.4% | 0.087 |
AF, atrial fibrillation; TIA, transient ischaemic attack; OAC, oral anticoagulant.
The P values compare each clinical characteristic for each non-warfarin OAC with the patients on warfarin.
*Statistically significant compared with the warfarin group.