Table 1.
Cell line survey for brevetoxin 2 (PbTx-2) cytotoxicity. EC50 values are calculated from the curves generated in Figure 1.
| Cell Line | Cell Type | Seeded Density | 24 h EC50 | 48 h EC50 | 72 h EC50 |
|---|---|---|---|---|---|
| B35 | Rat neuronal neuroblastoma | 5000 | 3.39 × 10−6 M | 6.40 × 10−7 M | 4.57 × 10−7 M |
| B50 | Rat neuronal neuroblastoma | 5000 | 5.24 × 10−6 M | 2.22 × 10−6 M | 2.70 × 10−6 M |
| BE(2)-M17 | Human neuroblastoma | 5000 | 2.60 × 10−6 M | 9.40 × 10−7 M | 8.77 × 10−7 M |
| Neuro-2A | Mouse neuronal neuroblastoma | 5000 | 3.66 × 10−6 M | 1.94 × 10−6 M | 2.18 × 10−6 M |
| PC-12 | Rat adrenal pheochromocytoma | 10,000 | 3.60 × 10−6 M | 2.92 × 10−6 M | 2.99 × 10−6 M |
| SH-SY5Y | Human bone marrow neuroblastoma | 5000 | 2.26 × 10−6 M | 1.14 × 10−6 M | 8.11 × 10−7 M |
| SJCRH30 | Human muscle rhabdomyosarcoma | 5000 | 1.70 × 10−6 M | 8.61 × 10−7 M | 7.69 × 10−7 M |