Table 3.

Grade ≥ 2 Toxicity Comparison Between Conventional RT and IMRT

Toxicity	Overall		Conventional RT		IMRT		P
	No.	%	No.	%	No.	%
Wound complications
Noninfected	28	8.8	14	9.1	14	8.5	1.0
Infected	30	9.4	13	8.4	17	10.3	.70
Radiation dermatitis	127	39.8	75	48.7	52	31.5	.002
Fracture	22	6.9	14	9.1	8	4.8	.18
Nerve damage*	7	2.6	2	1.6	5	3.5	.45
Joint stiffness	41	12.9	17	11	24	14.5	.40
Edema	36	11.3	23	14.9	13	7.9	.05

Abbreviations: IMRT, intensity-modulated radiation therapy; RT, radiation therapy.

^*Assessment of nerve damage was limited to patients who did not undergo nerve resection as part of their limb-sparing surgery (n = 269).