Table 1.
Characteristics of Cohort by Cystectomy Status
| Characteristic | All Patients | Cystectomy |
No Cystectomy |
|||
|---|---|---|---|---|---|---|
| No. | % | No. | % | P | ||
| Total | 50,520 | 4,878 | 10 | 45,642 | 90 | |
| Age at diagnosis, years | ||||||
| 66-69 | 7,069 | 1,000 | 21 | 6,069 | 13 | < .001 |
| 70-74 | 11,003 | 1,446 | 30 | 9,557 | 21 | |
| 75-79 | 12,652 | 1,369 | 28 | 11,283 | 25 | |
| ≥ 80 | 19,796 | 1,063 | 22 | 18,733 | 41 | |
| Sex | ||||||
| Male | 37,633 | 3,611 | 74 | 34,022 | 75 | NS |
| Female | 12,887 | 1,267 | 26 | 11,620 | 25 | |
| Race | ||||||
| White | 46,445 | 4,477 | 92 | 41,968 | 92 | NS |
| Black | 1,963 | 178 | 4 | 1,785 | 4 | |
| Hispanic | 572 | 67 | 1 | 505 | 1 | |
| Other | 1,540 | 156 | 3 | 1384 | 3 | |
| Census tract median income | ||||||
| 1st quartile | 11,765 | 1,107 | 23 | 10,658 | 23 | NS |
| 2nd quartile | 11,750 | 1,139 | 23 | 10,611 | 23 | |
| 3rd quartile | 11,751 | 1,112 | 23 | 10,639 | 23 | |
| 4th quartile | 12,110 | 1,218 | 25 | 10,892 | 24 | |
| Unknown | 3144 | 302 | 6 | 2,842 | 6 | |
| Urban-rural residence | ||||||
| Metropolitan | 42,941 | 4,098 | 84 | 38,843 | 85 | .042 |
| Nonmetropolitan | 7,579 | 780 | 16 | 6,799 | 15 | |
| Region | ||||||
| Northeast | 13,346 | 1,189 | 24 | 12,157 | 27 | .0055 |
| South | 8,211 | 804 | 16 | 7,407 | 16 | |
| Midwest | 7,612 | 738 | 15 | 6,874 | 15 | |
| West | 21,351 | 2,147 | 44 | 19,204 | 42 | |
| Married | ||||||
| Yes | 30,343 | 3,256 | 67 | 27,087 | 59 | < .001 |
| No | 17,213 | 1,431 | 29 | 15,782 | 35 | |
| Unknown | 2,964 | 191 | 4 | 2,773 | 6 | |
| Grade | ||||||
| 1 | 7,459 | 115 | 2 | 7,344 | 16 | < .001 |
| 2 | 16,821 | 596 | 12 | 16,225 | 36 | |
| 3 | 12,566 | 1,971 | 40 | 10,595 | 23 | |
| 4 | 9,425 | 1,874 | 38 | 7,551 | 17 | |
| Unknown | 4,249 | 322 | 7 | 3,927 | 9 | |
| AJCC stage | ||||||
| 0 | 15,187 | 379 | 8 | 14,808 | 32 | < .001 |
| I | 26,581 | 1,691 | 35 | 24,890 | 55 | |
| II | 5,858 | 1,440 | 30 | 4,418 | 10 | |
| III | 2,894 | 1,368 | 28 | 1,526 | 3 | |
| Lymph node involvement | ||||||
| Negative | 2,797 | 2,079 | 43 | 718 | 2 | < .001 |
| Unknown/not evaluated | 47,723 | 2,799 | 57 | 44,924 | 98 | |
| Chemotherapy | ||||||
| Systemic ± intravesical | 7368 | 949 | 19 | 6,419 | 14 | < .001 |
| Intravesical only | 1,932 | 114 | 2 | 1,818 | 4 | |
| None | 41,220 | 3,815 | 78 | 37,405 | 82 | |
| Charlson comorbidity score | ||||||
| 0 | 27,449 | 3,069 | 63 | 24,380 | 53 | < .001 |
| 1 | 12,717 | 1,133 | 23 | 11,584 | 25 | |
| ≥ 2 | 10,354 | 676 | 14 | 9,678 | 21 | |
| History of chronic kidney disease | ||||||
| Yes | 2,809 | 187 | 4 | 2,622 | 6 | < .001 |
| No | 47,711 | 4,691 | 96 | 43,020 | 94 | |
| History of fracture | ||||||
| Yes | 3,074 | 242 | 5 | 2,832 | 6 | < .001 |
| No | 47,446 | 4636 | 95 | 42,810 | 94 | |
| Urinary diversion | ||||||
| Continent | 721 | 721 | 15 | N/A | ||
| Incontinent | 3,892 | 3,892 | 80 | N/A | ||
| Unknown | 265 | 265 | 5 | N/A | ||
NOTE. P value for unadjusted association between characteristics and receipt of cystectomy. History of chronic kidney disease on the basis of diagnosis codes from inpatient and outpatient claims in year prior to bladder cancer diagnosis. History of fracture on the basis of diagnosis codes from inpatient and outpatient claims in the year prior to bladder cancer diagnosis or cystectomy.
Abbreviations: AJCC, American Joint Committee on Cancer; N/A, not applicable; NS, not significant.