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. Author manuscript; available in PMC: 2014 Sep 30.
Published in final edited form as: Pharm Res. 2006 Feb 2;23(4):670–679. doi: 10.1007/s11095-005-9608-3

Fig. 4.

Fig. 4

Time course of muscle GS mRNA and activity profiles in normal rats (circadian rhythm study) or following i.v. injection of 0.1 mg kg−1 dexamethasone or 50 mg kg−1 hydrocortisone in ADX rats (single bolus dose study). Symbols are mean data (± SD) and the lines are model-fitted profiles. The dashed line represents simulated plasma CS concentrations over the 24-h period. The shaded areas represent the dark period. Note differences in scales.