TABLE 2.
Effect of oxidative stress modulators on lipid peroxidation and polyphenol content in A. flavus
| Marker | Stage | Value with no modulatora | Value with indicated ROS modulatora |
Value with indicated TRS modulatora |
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Specific |
General |
||||||||||
| TIRON | DMSO | BHA | ATR | ASC | CAF | GSH | NAC | DTT | |||
| LOOHb | Control-SD | 1.7 ± 0.09 (1) | 1.3 ± 0.12 (0.8) | 1.52 ± 0.15 (1) | 1.26 ± 0.1 (0.7) | 1.37 ± 0.09 (0.8) | 1.42 ± 0.1 (0.8) | 1.14 ± 0.13 (0.7) | 1.22 ± 0.12 (0.7) | 0.63 ± 0.09 (0.4) | 0.22 ± 0.08 (0.1) |
| Control-UD | 0.89 ± 0.16 (0.5) | NA | NA | NA | NA | NA | NA | NA | NA | NA | |
| ΔveA-NSD | 0.49 ± 0.05 (0.3) | NA | NA | NA | NA | NA | NA | NA | NA | NA | |
| ΔveA-UD | 0.32 ± 0.03 (0.2) | NA | NA | NA | NA | NA | NA | NA | NA | NA | |
| FrMDAc | Control-SD | 373 ± 30 (1) | 360 ± 48 (1) | 398 ± 43 (1) | 270 ± 23 (0.7) | 261 ± 22 (0.7) | 333 ± 39 (1) | 291 ± 30 (1) | 255 ± 22 (0.7) | 270 ± 21 (0.7) | 168 ± 30 (0.5) |
| Control-UD | 320 ± 32 (1) | NA | NA | NA | NA | NA | NA | NA | NA | NA | |
| ΔveA-NSD | 380 ± 20 (1) | NA | NA | NA | NA | NA | NA | NA | NA | NA | |
| ΔveA-UD | 361 ± 28 (1) | NA | NA | NA | NA | NA | NA | NA | NA | NA | |
| PLPd | Control-SD | 446 ± 49 (1) | 10,921 ± 640 (25) | 2,145 ± 190 (4.8) | 440 ± 38 (1) | 2,391 ± 200 (5.4) | 2,197 ± 240 (5) | 788 ± 54 (1.8) | 245 ± 19 (0.6) | 241 ± 15 (0.5) | 818 ± 64 (1.8) |
| Control-UD | 1,096 ± 75 (2.5) | NA | NA | NA | NA | NA | NA | NA | NA | NA | |
| ΔveA-NSD | 422 ± 38 (1) | NA | NA | NA | NA | NA | NA | NA | NA | NA | |
| ΔveA-UD | 431 ± 42 (1) | NA | NA | NA | NA | NA | NA | NA | NA | NA | |
a
See footnote a of Table 1.
b
Lipid hydroperoxides (LOOH) in nmol cumene hydroperoxide equivalents/mg total fungal protein.
c
Free malondialdehyde (FrMDA) in pmol/mg total fungal protein
d
Polyphenols (PLP) in nmol caffeic acid equivalents/mg total fungal protein.