TABLE 2.
Clinical symptoms, pathological changes, and virus detection in pigs
| Virus | Infection characteristics in: |
|||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Directly infected pigs |
In-contact pigs |
|||||||||||
| Pyrexiaa (no. positive/total no.) | Nasal discharge (no. positive/total no.) | Wheezing/coughing (no. positive/total no.) | Pulmonary consolidationb (no. positive/total no.) (%) | Microscopic lung lesion scorec | Virus detection in lungd (no. positive/total no.) (titer) | Pyrexiaa (no. positive/total no.) | Nasal discharge (no. positive/total no.) | Pulmonary consolidationb (no. positive/total no.) (%) | Microscopic lung lesion scorec | Virus detection in lungd (no. positive/total no.) (titer) | Seroconversion (no. positive/total no.) | |
| L2 | 3/3 (40.4 ± 0.2) | 3/3 | 3/3 | 3/3 (23.2 ± 3.1) | 2.8 ± 0.1 | 3/3 (3.7 ± 0.3) | 3/3 (40.1 ± 0.2) | 3/3 | 3/3 (6.3 ± 1.6) | 1.5 ± 0.2 | 3/3 (2.2 ± 0.4) | 3/3 |
| N9 | 3/3 (40.3 ± 0.2) | 3/3 | 2/3 | 3/3 (19.6 ± 4.6) | 2.5 ± 0.1 | 3/3 (3.2 ± 0.4) | 3/3 (40.0 ± 0.2) | 3/3 | 3/3 (5.1 ± 2.8) | 1.7 ± 0.2 | 3/3 (2.1 ± 0.2) | 3/3 |
| L18 | 3/3 (40.3 ± 0.1) | 3/3 | 2/3 | 3/3 (22.3 ± 3.2) | 2.3 ± 0.3 | 3/3 (3.0 ± 0.1) | 3/3 (40.1 ± 0.1) | 3/3 | 3/3 (5.8 ± 2.3) | 1.1 ± 0.1 | 3/3 (2.8 ± 0.2) | 3/3 |
| rH1N1 | 1/3 (39.6 ± 0.2) | 3/3 | 0/3 | 1/3 (<1) | 0.3 ± 0.1 | 0/3 (<1)e | 0/3 (39.2 ± 0.1) | 0/3 | 0 | 0 | 0/3 (<1e) | 0/3 |
a
Rectal temperatures higher than 39.5°C are considered pyrexia in pigs. Peak rectal temperatures are expressed in parentheses as means ± standard deviations (SD).
b
The directly infected pigs were euthanized at 6 dpi and the in-contact pigs at 7 dpc (8 dpi). Percentages are based on the pulmonary consolidation area, and the values are expressed as mean percentages ± SD.
c
Microscopic lung lesions were assigned a score of 0 to 4. Scores are expressed as means ± SD.
d
Virus titers are expressed as mean log10 TCID50/g ± SD.
e
Lower than the detection limit of 10 TCID50/g.