TABLE 3.
Challenge virus and VRP typea | No. of survivors/total no. of mice in group by time of challenge (mos.)b |
|||
---|---|---|---|---|
1.5 | 2 | 6 | 12 | |
VEEV-IAB | ||||
VEEV | 1/10 | 10/10 | 10/10 | 10/10 |
V/W/E | 1/10 | 10/10 | 6/10 | 8/9 |
Control | 0/5 | 0/5 | 0/5 | 0/4 |
Mock | 0/5 | 0/5 | 0/5 | 0/5 |
VEEV-IE | ||||
VEEV | 2/10 | 10/10 | 9/10 | 10/10c |
V/W/E | 3/10 | 10/10 | 10/10 | 7/9c |
Control | 0/5 | 0/5 | 0/5 | 0/5 |
Mock | 0/5 | 0/5 | 0/5 | 0/5 |
VEEV-IIIA | ||||
VEEV | 4/10 | 9/9 | 10/10 | 10/10c |
V/W/E | 1/10 | 11/11 | 10/10 | 9/9c |
Control | 0/5 | 0/5 | 0/5 | 0/5 |
Mock | 0/5 | 0/5 | 0/5 | 0/5 |
Aerosol challenge.
Time of challenge is indicated as time post-priming vaccination.
Nonlethal illness observed.