TABLE 4.
Summary of EEEV-GP and WEEV-GP VRP duration of protection study
| Challenge virus and VRP typea | No. of survivors/total no. of mice in group by time of challenge (mos.)b |
|||
|---|---|---|---|---|
| 1.5 | 2 | 6 | 12 | |
| EEEV | ||||
| EEEV | 0/10 | —c | 10/10 | 10/10 |
| V/W/E | 0/10 | 10/10 | 9/9 | 9/10 |
| Control | 0/10 | 0/10 | 0/9 | 0/9 |
| WEEV | ||||
| WEEV | 2/10 | 10/10 | 10/10 | 9/9 |
| V/W/E | 1/10 | 10/10 | 9/10 | 7/8 |
| Control | 0/10 | 0/10 | 0/10 | 0/10 |
a
Aerosol challenge.
b
Time of challenge is indicated as time post-priming vaccination.
c
Experimental group removed from study due to pregnancy in cohort of animals.