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(A) pUL42 residue V296 (red) is located next to the interface of pUL42 (molecular surface in blue) and the bound C-terminal tail of the viral DNA polymerase catalytic subunit (ribbon diagram in green) (RCSB PDB accession code 1DML) (32). (B) V296 is mutated to Ile (stick model in red) in pUL42 (ribbon diagram in blue), showing no steric clash with binding of the DNA polymerase C-terminal tail (molecular surface in green). The two panels are in the same view.
