TABLE 2.

Number of immune cells in the spleens of WT and Irf5^−/− mice at day 2 after WNV infection^a

Cell type	Mean no. of cells ± SD		P
	WT mice	Irf5−/− mice
CD19+ B cells	2.2 × 107 ± 2.0 × 106	2.3 × 107 ± 2.1 × 1046	0.67
CD4+ T cells	9.2 × 106 ± 1.0 × 106	1.1 × 107 ± 7.8 × 105	0.25
CD8+ T cells	5.8 × 106 + 5.7 × 105	6.4 × 106 ± 2.9 × 105	0.20
NK1.1+ NK cells	1.7 × 106 ± 2.1 × 105	1.8 × 106 ± 2.1 × 105	0.91
CD11c+ DCs	4.2 × 104 ± 7.5 × 103	6.5 × 104 ± 1.0 × 104	0.07
Lys6G+ granulocytes	6.2 × 105 ± 1.7 × 105	1.0 × 106 ± 4.8 × 105	0.43

^aSplenocytes were collected from WT and Irf5^−/− mice 2 days after WNV infection. Cells were phenotyped (see Materials and Methods) and processed by flow cytometry. The results are the averages from five to seven mice per group. None of the differences between groups attained statistical significance (P > 0.05). DCs, dendritic cells.