FIG 5.

CNV VLP binding to canine and human saliva samples. (A) ELISA plates were coated with 26 canine saliva samples with characterized phenotypes (A antigen and Lewis), and the abilities of CNV VLPs (strain C33) to bind were assessed. The samples are ordered according to their CNV VLP binding abilities (low to high). Lewis antigen expression is not shown. (B) Six human saliva samples, each with a different ABO and Lewis phenotype, were used to assess binding of CNV VLPs from the three CNV strains available. (C) CNV strain C33 was next selected as the representative strain to analyze binding to a wider panel of 26 human saliva samples. Le, Lewis antigen.