TABLE 1.
Summary of polarization phenotypes of MLV mutants in virological synapses (VS) in fibroblasts and at uropod
| MLV | Polarization |
Polarization index (uropod localization) (n = 10) |
||
|---|---|---|---|---|
| VS in fibroblastsa | Uropod | Mean | SEM | |
| Wild type (T cells) | + | + | 6.75 | 2.44 |
| Wild type (B cells) | + | + | 9.63 | 1.46 |
| ΔEnv | − | + | 10.90 | 1.80 |
| G2A | − | − | 0.91 | 0.06 |
| SrcΔMA | + | + | 5.38 | 1.03 |
| ΔP12 | + | + | 44.32 | 5.50 |
| ΔCA | + | − | 1.43 | 0.05 |
| ΔCA-CTD | + | − | 1.37 | 0.12 |
| ΔNC | + | + | 3.53 | 0.56 |
| SrcΔMAΔNC | − | − | 1.41 | 0.06 |
| SrcΔMAΔNCLZ | + | + | 7.92 | 1.75 |
| SrcNC | + | − | 1.39 | 0.03 |
| LckΔMA | − | + | 8.03 | 2.28 |
| Srcbm | + | + | 6.56 | 1.29 |
| Lckbm | − | + | 7.42 | 0.94 |
| bm | − | + | 3.45 | 0.46 |
| ΔPPPY | + | + | 14.18 | 2.50 |
a
Determined by Li et al. (56). VS, virological synapses.