Skip to main content
. 2014 Sep;88(18):10680–10695. doi: 10.1128/JVI.01176-14

FIG 6.

FIG 6

Mo-MuLVLUC and Mo-MuLVLUC/PBSQ have the same infection titers. (A) RAT2 cells lack PBS-mediated silencing activity (32) and were used to normalize the titer of Mo-MuLV/LUC and Mo-MuLV/LUC/PBSQ. (B) The relative luciferase activity showed no infection activity differences between Mo-MuLVLUC and Mo-MuLVLUC/PBSQ in wild-type RAT2 cells or RAT2 cells transfected with either the wild type or the indicated mutant DNMT3L expression constructs. (C) DNMT3L did not induce the DNA methylation of the proviral LTR sequence in RAT2 cells 20 days postinfection.