FIG 2.
Protective capacity of low-dose MVA immunization against a lethal mousepox challenge infection. C57BL/6 mice were challenged with ECTV 2 days after immunization with MVA vaccine (104 to 108 PFU) or PBS (mock-vaccinated animals, used as controls). In all experiments, weight loss of individual mice was monitored daily (5 per group). Error bars indicate standard errors of the means (SEMs), and the numbers of surviving/total animals are given in parentheses. *, P < 0.05; ***, P < 0.001. Data are representative of two or three experiments.