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. 2014 Sep;88(18):10946–10957. doi: 10.1128/JVI.00945-14

FIG 8.

FIG 8

MVA-primed CD8+ T cell responses are efficiently boosted upon ECTV challenge infection. (A and B) Virus-specific CD8+ T cells in C57BL/6 (A) and IFNAR−/− (B) mice after MVA immunization or MVA immunization and ECTV challenge infection, as measured by IFN-γ ELISPOT at day 8 after vaccination. (C and D) FACS analysis of B8R+ multimer-binding CD8+ T cells after MVA vaccination or vaccination and ECTV infection in C57BL/6 (C) and IFNAR−/− (D) mice, measured on day 8 after MVA immunization. Data are representative of three similar experiments (5 mice per group). **, P < 0.01.