Figure 2.

(a) Admissibility as a function of SNR for simulated in vivo and ex vivo tumor MET₂ data (using Eq. [1] and the parameters listed in Table 1). For ex vivo data, the admissibility for resolving all three observed components (3 comp) as well as resolving the short-lived component from the two longer-lived components (2 comp) was tabulated. The approximate range of experimental SNRs for voxel- and ROI-based analyses in vivo (hatched boxes) and ex vivo (grey boxes) is also indicated. (b) Admissibility as a function of p_I for simulated in vivo data (SNR = 800).