Table 5.

Involution after Initial Ablation for All Tumors

Parameter	Time since Cryotherapy
	Baseline	< 1.5 mo	4.5 mo	9 mo	15 mo	21 mo	≥ 27 mo
No. of tumors	263*	151	100	83	41	15	30
Initial tumor volume (cm3)	90.4	–	–	–	–	–	–
Ablation zone volume (cm3)	208.4	149.0	84.1	53.8	25.6	14.5	20.3
Tumor volume reduction (cm3)	–	59.5	124.4	154.6	182.8	193.9	188.09
Resorption (%)	–	28.5	59.7	74.2	87.7	93.0	90.3

Whereas ablation volume had been reduced to half at 4.5 mo, maximal involution was approached by 15 mo.

^*Baseline tumor count of 263 is higher than the actual number of tumors in the study because tumors treated repeatedly were used for resorption calculations only until the time of the subsequent procedure, at which time a new unique value was associated with that tumor and its respective involution observations.