TABLE 4.
Antibody | MMR Before Randomized Treatment? | Visit | Number (%) of Participants With Protective Antibody Levels | ||
---|---|---|---|---|---|
HU | Placebo | P (Fisher’s exact test) | |||
Measles | Yes | 2–10 wk after MMR | 23/24 (95.8) | 10/11 (90.9) | .536 |
Age 24 mo | 40/40 (100.0) | 31/31 (100.0) | — | ||
End of study | 36/36 (100.0) | 28/29 (96.6) | .446 | ||
No | 2–10 wk after MMR | 10/14 (71.4) | 24/24 (100.0) | .014 | |
Age 24 mo | 18/19 (94.7) | 28/28 (100.0) | .404 | ||
End of study | 21/21 (100.0) | 27/27 (100.0) | — | ||
Mumps | Yes | 2–10 wk after MMR | 23/24 (95.8) | 9/11 (81.8) | .227 |
Age 24 mo | 40/41 (97.6) | 27/31 (87.1) | .158 | ||
End of study | 37/38 (97.4) | 26/29 (89.7) | .308 | ||
No | 2–10 wk after MMR | 11/14 (78.6) | 22/24 (91.7) | .337 | |
Age 24 mo | 19/21 (90.5) | 28/29 (96.6) | .565 | ||
End of study | 19/21 (90.5) | 28/30 (96.7) | .561 | ||
Rubella | Yes | 2–10 wk after MMR | 24/25 (96.0) | 10/13 (76.9) | .107 |
Age 24 mo | 36/36 (100.0) | 24/24 (100.0) | — | ||
End of study | 33/33 (100.0) | 22/22 (100.0) | — | ||
No | 2–10 wk after MMR | 10/15 (66.7) | 23/25 (92.0) | .081 | |
Age 24 mo | 15/16 (93.8) | 26/26 (100.0) | .381 | ||
End of study | 17/18 (94.4) | 26/26 (100.0) | .409 |
HU, hydroxyurea.
No P value calculated (—) when hydroxyurea and placebo % protected = 100%.