Figure 5. Group 1 Env-specific antibody responses stratified by pre-existing reciprocal 90% Ad5 neutralization titers.

Antibody responses were measured using ELISA against HIV-1 envelope proteins matching vaccine antigen. Data from 4 weeks post rAd5 vaccine is shown as individual data points and box plots showing the median, 25^th and 75^th quartiles for group 1 stratified by reciprocal dilution 90% Ad5 neutralization titer. A comparison of Biojector and N/S mode of delivery is shown. Red represents the responders and blue represents the non-responders. Anti-EnvA binding antibody levels are plotted as log 10 of ELISA titer, and are shown as representative of responses to EnvB and EnvC.