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. 2013 Dec 13;63(1):270–281. doi: 10.2337/db13-0890

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© 2014 by the American Diabetes Association.

Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. See http://creativecommons.org/licenses/by-nc-nd/3.0/ for details.

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Quantitative measurement of sodium nitrite–mediated vascular density and cell proliferation. A: The panel reports quantitative measurement of the angiogenic index (CD31/DAPI ratio) from gastrocnemius muscle of ischemic (Isch) and nonischemic (NI) control (PBS)- and sodium nitrite (Nitrite)–treated diabetic mice from Fig. 1A, protocol schematic. B: The panel shows the quantitative measurement of the proliferation index (Ki67/DAPI ratio) from gastrocnemius muscle of Isch and NI control (PBS)- and sodium nitrite (Nitrite)–treated diabetic mice from Fig. 1A, protocol schematic. C: The panel reports the angiogenic index (CD31/DAPI ratio) from gastrocnemius muscle of Isch and NI control (PBS)- and sodium nitrite (Nitrite)–treated diabetic mice from Fig. 1C, protocol schematic. D: The panel illustrates the proliferation index (Ki67/DAPI ratio) from gastrocnemius muscle of Isch and NI control (PBS)- and sodium nitrite (Nitrite)–treated diabetic mice from Fig. 1C, protocol schematic. n = 10/cohort. *P < 0.05.