. 2014 Sep 29;55(9):6101–6107. doi: 10.1167/iovs.14-14958

Table 2.

Logistic Regression Results for Variants in the Target Region

Chromosome	Base Pair	Reference Allele	Alternate Allele	dbSNP Identifier	SNV vs. Insertion/ Deletion (Indel)	Alternate Allele Frequency		Odds Ratio	Confidence Range	P
Chromosome	Base Pair	Reference Allele	Alternate Allele	dbSNP Identifier	SNV vs. Insertion/ Deletion (Indel)	Fuchs'	Control	Odds Ratio	Confidence Range	P
18	53210302	`G`	`T`	rs613872	SNV	0.4779	0.125	12.04	3.2–47.2	0.0004
18	53244414	`A`	`T`	rs2924322	SNV	0.3731	0.1	10.25	2.1–49.2	0.004
18	53244442	`TAA`	`T`	rs33980799	Indel	0.375	0.125	7.0	1.8–26.9	0.005
18	53248151	`T`	`C`	rs618869	SNV	0.375	0.125	7.0	1.8–26.9	0.005
18	53264343	`A`	`G`	rs596668	SNV	0.375	0.125	7.0	1.8–26.9	0.005
18	53252388	`G`	`A`	rs599550	SNV	0.375	0.1562	7.0	1.8–26.9	0.005
18	53308061	`AT`	`A`	rs59006454	Indel	0.6912	0.4375	7.273	1.7–31.4	0.008
18	53276116	`T`	`A`	rs12458118	SNV	0.6912	0.4375	7.273	1.7–31.4	0.008
18	53276523	`G`	`A`	rs9951280	SNV	0.6912	0.4375	7.273	1.7–31.4	0.008
18	53299460	`G`	`A`	rs12103984	SNV	0.6912	0.4375	7.273	1.7–31.4	0.008
18	53315397	`T`	`A`	rs17089911	SNV	0.6912	0.4375	7.273	1.7–31.4	0.008
18	53270531	`T`	`C`	rs682245	SNV	0.6912	0.4688	7.273	1.7–31.4	0.008
18	53292908	`T`	`C`	rs8090341	SNV	0.6985	0.4375	7.273	1.7–31.4	0.008
18	53296927	`G`	`A`	rs12457157	SNV	0.6985	0.4375	7.273	1.7–31.4	0.008
18	53301527	`A`	`C`	rs6566169	SNV	0.6985	0.4375	7.273	1.7–31.4	0.008
18	53303546	`T`	`G`	rs35691742	SNV	0.6985	0.4375	7.273	1.7–31.4	0.008
18	53186092	`T`	`C`	rs627685	SNV	0.7868	0.5938	7.615	1.2–50.2	0.035
18	53204136	`A`	`C`	rs658905	SNV	0.5147	0.4375	3.291	1.0–10.5	0.044
18	52904858	`G`	`GC`	rs36069440	Indel	0.2721	0.09375	3.852	1.0–14.7	0.049
18	53178061	`G`	`A`	rs67387556	SNV	0.6176	0.625	4.2	1.0–18.0	0.053
18	53284109	`A`	`G`	rs616580	SNV	0.3088	0.5625	0.2923	0.1–1.1	0.073
18	53287570	`C`	`T`	rs1642313	SNV	0.3088	0.5625	0.2923	0.1–1.1	0.073
18	53294569	`T`	`C`	rs644279	SNV	0.3088	0.5625	0.2923	0.1–1.1	0.073
18	53193029	`C`	`CT`	rs11441646	Indel	0.4853	0.4062	2.748	0.9–8.6	0.083
18	53190188	`G`	`A`	rs9948513	SNV	0.4853	0.4062	2.748	0.9–8.6	0.083

A dominant model association test was performed for each variant shown. Logistic regression statistics and odds ratios for FECD are shown for the 25 variants with the lowest P values. The SNV that confers the highest odds ratio for FECD is rs613872, with an odds ratio of 12 in these samples.