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Comparison of Similarity Factors (f 2) for Aqueous Ethylcellulose Coated HCTZ Matrix Tablets
| Stability condition | Duration | Starch 1500 | Lactose |
|---|---|---|---|
| 40°C/75% RH | 3 months | 85 | 77 |
| 6 months | 65 | 64 | |
| 30°C/65% RH | 3 months | 94 | 60 |
| 6 months | 63 | 52 |
Release profiles for each filler at initial time point was considered as reference
