Table I.
Properties of Amoxicillin, Metronidazole, and Zidovudine Formulations of This Study
| Drug name | Brand name | Manufacturer | Country | Dosage form | Expiry date | Lot number | Excipients | Is/was on formulary |
|---|---|---|---|---|---|---|---|---|
| Metronidazole USP | Gendazole® 200 mg | Genethics Pharmaceutical Limited | Republic of Trinidad and Tobago | Film-coated tablet | October 2012 | MNO-905 | Maize starch, microcrystalline cellulose, maize starch for paste, gelatine, povidone, methyl hydroxybenzoate sodium, propyl hydroxybenzoate sodium, purified water, magnesium stearate, purified talc, colloidal anhydrous silica, sodium starch glycollate, coating materials: instacoat white (color: titanium dioxide), isopropyl alcohol, dichloromethane | Yes |
| Metronidazole B.P. | Metrogyl® 200 mg | Unique Pharmaceutical Labs | India | Film-coated tablet | September 2014 | B.No.AM69006 | Lactose, disodium edentate, ethyl cellulose, sodium starch glycollate, silica-colloidal anhydrous, guar gum, magnesium stearate | Yes |
| Metronidazole USP | Gendazole F® 400 mg | Genethics Pharmaceutical Limited | Republic of Trinidad and Tobago | Film-coated tablet | January 2014 | MoZ-11029 | Maize starch, microcrystalline cellulose, maize starch for paste, gelatine, povidone, methyl hydroxybenzoate sodium, propyl hydroxybenzoate sodium, purified water, magnesium stearate, purified talc, colloidal anhydrous silica, sodium starch glycollate, coating materials: instacoat white (color: titanium dioxide), isopropyl alcohol, dichloromethane | Yes |
| Metronidazole B.P. | Metrogyl® 400 mg | Unique Pharmaceutical Labs. | India | Film-coated tablet | August 2013 | B.No. AMA8003 | Lactose, disodium edentate, ethyl cellulose, sodium starch glycollate, silica-colloidal anhydrous, guar gum, magnesium stearate, quinoline yellow ci 47005 (e104) | Yes |
| Zidovudine | Aviro-Z® 300 mg | Ranbaxy Laboratories Limited | India | Film-coated tablet | May 2013 | 2307512 | Information for excipients was not available | Yes |
| Amoxicillin trihydrate BP | Imox®-500 mg | Ipca Laboratories Limited | India | Capsule | March 2015 | B. No. LNo21004 | Information for excipients was not available | No |
| Amoxicillin trihydrate BP | Imox® 250 mg | Ipca Laboratories Limited | India | Capsule | June 2015 | B. No. PU031004 | Information for excipients was not available | Yes |
| Amoxicillin trihydrate BP | Pulmoxyl®-250 mg | Micro Labs Limited | India | Capsule | May 2014 | PXTB0082 | Information for excipients was not available | Yes |
| Amoxicillin B.P. | Ospamox® 250 mg | Sandoz | Austria | Capsule | October 2012 | 159920 | Gelatin, magnesium stearate, microcrystalline cellulose | Yes |
| Amoxicillin trihydrate | Ospamox® 500 mg | Sandoz GmbH | Austria | Film-coated tablet | September 2014 | BD3103 | Magnesium stearate, povidine, carboxymethyl starch, microcrystalline cellulose, titanium dioxide (e-171), talc, hydroxypropylmethyl cellulose | No |
| Amoxicillin trihydrate BP | Ranoxyl® 500 mg | Ranbaxy | India | Capsule | January 2014 | 2250897 | Information for excipients was not available | No |
| Amoxicillin trihydrate BP | Ranoxyl® 250 mg | Ranbaxy | India | Capsule | September 2013 | B. No. 2211609 | Information for excipients was not available | Yes |
| Amoxicillin B.P. | Amoxil® 500 mg | SmithKline Beecham plc | UK | Capsule | February 2015 | 473620 | Information for excipients was not available | No |