Table II.

Downregulated proteins in renal tissue of immunoglobulin A (IgA) nephropathy patients.

No.	Accession no.	Protein name	Molecular function	Cellular component	Biological process	Peptides	Ratio
1	sp|P09669	Cytochrome c oxidase subunit 6C	Oxidoreductase activity	Membrane- bound organelle	Cellular metabolic process	3	0.62
2	sp|P00403	Cytochrome c oxidase subunit 2	Oxidoreductase activity	Organelle membrane	Oxidation reduction	6	0.56
3	sp|P51649	Succinate- semialdehyde dehydrogenase, mitochondrial	Oxidoreductase activity	Cell fraction	Oxidation reduction	4	0.55
4	sp|P10809	60 kDa heat shock protein, mitochondrial	Nucleotide binding	Organelle lumen	Positive regulation of immune system process	47	0.53
5	sp|P62195	26S protease regulatory subunit 8	Nucleoside binding	Protein complex	Catabolic process	1	0.50
6	sp|P05091	Aldehyde dehydrogenase, mitochondrial	Oxidoreductase activity	Organelle lumen	Oxidation reduction	28	0.47
7	sp|P01031	Complement C5	Protein binding	Protein complex	Cellular metabolic process	4	0.45
8	sp|P30837	Aldehyde dehydrogenase X, mitochondrial	Oxidoreductase activity	Intracellular	Oxidation reduction	7	0.44
9	sp|P61604	10 kDa heat shock protein, mitochondrial	Nucleotide binding	Intracellular organelle	Response to chemical stimulus	11	0.36
10	sp|P02753	Retinol-binding protein 4	Lipid binding	Extracellular region	Response to external stimulus	11	0.36
11	sp|P00966	Argininosuccinate synthase	Nucleoside binding	Intracellular	Cellular metabolic process	21	0.36
12	sp|P05062	Fructose- bisphosphate aldolase B	Lyase activity	Non-membrane- bound organelle	Catabolic process	53	0.25