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. 2014 Sep 30;5:475. doi: 10.3389/fimmu.2014.00475

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Copyright © 2014 Alural, Duran, Tufekci, Allmer, Onkal, Tunali, Genc and Genc.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Upregulation of miR-451 and miR-885-5p reduces proliferation of SH-SY5Y cells enhanced by EPO. In miRNA mimic transfected and non-transfected cells, cell proliferation was observed by counting cells using phase-contrast microscopy following either 24 or 48 h EPO treatment. (A) Cell counts and (B) phase-contrast microscopy images. Transfection of miR-451 and miR-885-5p mimics reduces the proliferative effect of EPO. EPO; erythropoietin. The data are presented as mean ± SE, n = 5 (*p < 0.05).