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. 2014 Sep 30;8:340. doi: 10.3389/fnbeh.2014.00340

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Copyright © 2014 Khemissi, Farooq, Le Guisquet, Sakly and Belzung.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution and reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of UCMS and 4 week treatment with fluoxetine (15 mg/kg/day) on the dexamethasone (DEXA) suppression test after vehicle or dexamethasone injection. HS: High suppressers, LS: Low suppressers, VEH: vehicle, FLX: fluoxetine. (A) Corticosterone after injection of vehicle or dexamethasone after 2 weeks of UCMS. (B) Suppression rate of corticosterone after 2 weeks of UCMS. (C) Corticosterone after injection of vehicle or dexamethasone at the end of UCMS. (D) Suppression rate after 9 weeks of UCMS. Figures 4A,B: n = 17 in each experimental condition. Figures 4C,D: HS VEH (n = 10), HS FLX (n = 7), LS VEH (n = 11), LS FLX (n = 6). HS vs. the corresponding LS condition: ^&&& p < 0.001; basal corticosterone vs. corresponding dexamethasone-induced corticosterone: ^$ p < 0.05, ^$$ p < 0.01, ^$$$ p < 0.001.