Table I.
The relative baseline tension of aortic rings treated with cisplatin.
| Thoracic aortic rings | Control (n) | Cisplatin (n) | |||
|---|---|---|---|---|---|
|
| |||||
| 10 μM | 100 μM | 200 μM | 500 μM | ||
| +E | 0.018±0.036 (6) | 0.033±0.045 (5) | 0.073±0.054 (6) | 0.091±0.063 (6) | 0.059±0.034 (5) |
| −E | 0.033±0.052 (9) | 0.037±0.050 (5) | 0.056±0.058 (6) | 0.021±0.045 (7) | 0.063±0.069 (5) |
Thoracic aortic rings (+E, endothelium-intact thoracic aorta; −E, endothelium-denuded thoracic aorta) were incubated in various concentrations of cisplatin (μM) for 6 h. Relative tensions of aortic rings were evaluated by ex vivo perfusion. Data are expressed as mean ± SEM.