Table I.

Cytokine concentrations in the kidney of uninfected mice and mice infected systemically with C. albicans at 24 and 72 h post-infection by cytometric bead array analysis.

Kidney	Uninfected group, mean ± SEM	24 h post-infection with C. albicans		72 h post-infection with C. albicans
		Mean ± SEM	P-value	Mean ± SEM	P-value
IFN-γ	9.06±2.35	3.18±2.13	0.115	11.90±2.04	0.334
IL-10	137.90±34.85	144.50±37.73	1.000	95.16±33.63	0.470
IL-17a	14.13±1.61	18.17±5.47	0.590	16.59±2.31	0.520
IL-2	21.40±1.82	21.58±5.10	0.570	20.62±4.70	0.630
IL-4	15.47±5.34	6.98±3.60	0.140	12.69±5.86	0.280
IL-6	19.46±4.67	265.90±44.28	0.002	6513.00±3356.00	0.002
TNF-α	34.26±10.00	549.90±53.39	0.002	3551.00±1418.00	0.002

Results are expressed as mean ± standard error of the mean (SEM) and the concentration of each cytokine measured is expressed in pg/g of kidney tissues. P<0.05 was considered to indicate a statistically significant difference. C. albicans, Candida albicans; IFN-γ, interferon-γ; IL, interleukin; TNF-α, tumor necrosis factor-α.