Table IV.
Cytokine concentrations in the kidney, spleen and brain homogenates of uninfected mice and mice infected systemically with C. albicans at 72 h post-infection by ELISA analysis.
| Organ | Uninfected, mean ± SEM | 72 h post-infection with C. albicans, mean ± SEM | P-value |
|---|---|---|---|
| Kidney | |||
| TGF-β | 201.40±6.75 | 285.20±7.52 | 0.002 |
| CXCL-1 | 1056.00±160.00 | 1942.00±206.90 | 0.015 |
| Spleen | |||
| TGF-β | 155.00±9.74 | 175.50±10.97 | 0.240 |
| CXCL-1 | 380.80±21.61 | 368.10±21.31 | 0.818 |
| Brain | |||
| TGF-β | 217.50±6.97 | 271.70±2.58 | 0.002 |
| CXCL-1 | 484.10±26.71 | 462.70±44.07 | 0.699 |
Results are expressed as mean ± standard error of the mean (SEM). Cytokine concentration of TGF-β (ng/g) and CXCL-1 (pg/g) in kidney, spleen and brain tissues. P<0.05 was considered to indicate a statistically significant difference. C. albicans, Candida albicans; TGF-β, transforming growth factor-β.