Figure 6.

Antitumor effect of CIGB-300, cisplatin (CDDP) or their combinations, in a cervical cancer model based on the inoculation of SiHa cells in nude mice. Once the tumor mass reached 30 mm³ (day 0), the mice were randomized into groups and injected with CIGB-300, cisplatin or their combinations at indicated doses, according to schemes A and B described in Materials and methods. (A and B) Tumor growth and Kaplan-Meier survival curves obtained from treated animals in scheme A. (C and D) Tumor growth and survival curves obtained from treated animals in scheme B.