Table II.
Mean serum lipoprotein levels by APOE genotype in breast cancer patients and healthy controlsa.
| APOE genotype | No. (%) | Total cholesterol (mg/dl) Mean (SD) |
HDL cholesterol (mg/dl) Mean (SD) |
LDL cholesterolb (mg/dl) Mean (SD) |
Triglycerides (mg/dl) Mean (SD) |
|---|---|---|---|---|---|
| Total sample (n=212) | |||||
| 2/3 | 20 (9.4) | 210.3 (47.9) | 56.0 (21.1) | 121.7 (44.9) | 162.7 (103.3) |
| 2/4 | 17 (8.1) | 185.0 (32.7) | 53.6 (11.2) | 100.7 (31.3) | 153.2 (83.1) |
| 3/3 | 119 (56.1) | 201.3 (45.8) | 51.4 (14.6) | 116.7 (44.8) | 165.8 (84.0) |
| 3/4 | 52 (24.5) | 216.9 (52.4) | 50.1 (13.8) | 128.9 (53.2) | 189.2 (155.2) |
| 4/4 | 4 (1.9) | 187.2 (22.1) | 48.5 (11.1) | 90.2 (56.3) | 242.7 (123.9) |
| Cases (n=47) | |||||
| 2/3 | 4 (8.5) | 253.5 (72.5) | 51.0 (14.1) | 166.3 (56.4) | 181.0 (159.3) |
| 3/3 | 28 (59.6) | 189.9 (55.2) | 48.4 (12.1) | 109.7 (51.4) | 159.1 (61.8) |
| 3/4 | 12 (25.5) | 194.7 (50.3) | 50.2 (15.2) | 106.5 (56.4) | 190.3 (241.1) |
| 4/4 | 3 (6.4) | 195.3 (18.4) | 43.7 (6.6) | 114.2 (35.9) | 187.3 (67.9) |
| Controls (n=165) | |||||
| 2/3 | 16 (9.7) | 199.5 (35.2) | 57.2 (22.7) | 110.6 (35.4) | 158.1 (91.3) |
| 2/4 | 17 (10.3) | 185.0 (32.6) | 53.6 (11.1) | 100.7 (31.3) | 153.2 (83.1) |
| 3/3 | 91 (55.2) | 204.8 (42.3) | 52.3 (15.2) | 118.9 (42.6) | 167.8 (89.9) |
| 3/4 | 40 (24.2) | 223.6 (51.8) | 50.1 (13.6) | 135.7 (50.9) | 188.8 (122.8) |
| 4/4 | 1 (0.6) | 163 | 63 | 180.2 | 409.0 |
a
In Control Group (4/4) it was shown absolute number for serum lipoproteins.
b
Based on Friedewald’s equation: LDLCHOL = TotalCHOL-HDLCHOL-(TG/5).
APOE, apolipoprotein E; LDL, low-density lipoprotein; HDL, high-density lipoprotein; TG, triglycerides; SD, standard deviation.