Table IV.
Allele and genotype distribution in breast cancer patients and healthy controls.
| Allele/genotype | Cases (n=47) No. (%) |
Controls (n=165) No. (%) |
Total (n=212) No. (%) |
P-valuea |
|---|---|---|---|---|
| Alleles | 0.019 | |||
| e2 | 4 (4.2) | 33 (10) | 37 (8.7) | |
| e3 | 72 (76.7) | 238 (72.1) | 310 (73.1) | |
| e4 | 18 (19.1) | 59 (17.9) | 77 (18.2) | |
| Genotypes | 0.172 | |||
| e2 carriers | 4 (8.5) | 33 (20) | 37 (17.4) | |
| e3 carriers | 28 (59.6) | 91 (55.1) | 119 (56.1) | |
| e4 carriers | 15 (31.9) | 41 (24.9) | 56 (26.5) |
a
Chi-square test. The e2 carriers included the genotypes e2/e2, e2/e3 and e2/e4; the e3 carriers included e3/e3; the e4 carriers included e3/e4 and e4/e4.
APOE, apolipoprotein E.